Does METHOTREXATE Cause Hypersensitivity? 9,799 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 9,799 reports of Hypersensitivity have been filed in association with METHOTREXATE (Methotrexate). This represents 3.9% of all adverse event reports for METHOTREXATE.
9,799
Reports of Hypersensitivity with METHOTREXATE
3.9%
of all METHOTREXATE reports
1,611
Deaths
3,474
Hospitalizations
How Dangerous Is Hypersensitivity From METHOTREXATE?
Of the 9,799 reports, 1,611 (16.4%) resulted in death, 3,474 (35.5%) required hospitalization, and 2,001 (20.4%) were considered life-threatening.
Is Hypersensitivity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 9,799 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Hypersensitivity?
ETANERCEPT (10,846)
ADALIMUMAB (10,641)
TOCILIZUMAB (9,076)
ABATACEPT (8,945)
INFLIXIMAB (8,519)
RITUXIMAB (8,408)
ADAPALENE (8,356)
LEFLUNOMIDE (7,926)
CERTOLIZUMAB PEGOL (7,353)
HYDROXYCHLOROQUINE (6,857)
Which METHOTREXATE Alternatives Have Lower Hypersensitivity Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA