Does AMITRIPTYLINE Cause Serotonin syndrome? 579 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 579 reports of Serotonin syndrome have been filed in association with AMITRIPTYLINE (AMITRIPTYLINE HYDROCHLORIDE). This represents 2.8% of all adverse event reports for AMITRIPTYLINE.
579
Reports of Serotonin syndrome with AMITRIPTYLINE
2.8%
of all AMITRIPTYLINE reports
27
Deaths
377
Hospitalizations
How Dangerous Is Serotonin syndrome From AMITRIPTYLINE?
Of the 579 reports, 27 (4.7%) resulted in death, 377 (65.1%) required hospitalization, and 166 (28.7%) were considered life-threatening.
Is Serotonin syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMITRIPTYLINE. However, 579 reports have been filed with the FAERS database.
What Other Side Effects Does AMITRIPTYLINE Cause?
Toxicity to various agents (3,001)
Drug ineffective (2,344)
Completed suicide (1,678)
Off label use (1,588)
Pain (1,300)
Fall (1,216)
Hypotension (1,205)
Drug abuse (1,116)
Dizziness (1,041)
Constipation (1,035)
What Other Drugs Cause Serotonin syndrome?
VENLAFAXINE (1,632)
SERTRALINE (1,563)
FLUOXETINE (1,457)
DULOXETINE (1,352)
TRAMADOL (1,229)
BUPROPION (1,058)
ESCITALOPRAM OXALATE (1,051)
QUETIAPINE (947)
TRAZODONE (831)
FENTANYL (778)
Which AMITRIPTYLINE Alternatives Have Lower Serotonin syndrome Risk?
AMITRIPTYLINE vs AMITRIPTYLINE\PERPHENAZINE
AMITRIPTYLINE vs AMIVANTAMAB
AMITRIPTYLINE vs AMIVANTAMAB-VMJW
AMITRIPTYLINE vs AMLODIPINE
AMITRIPTYLINE vs AMLODIPINE BESILATE