Does AMPHOTERICIN B Cause Bone marrow failure? 58 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 58 reports of Bone marrow failure have been filed in association with AMPHOTERICIN B (Amphotericin B). This represents 0.5% of all adverse event reports for AMPHOTERICIN B.
58
Reports of Bone marrow failure with AMPHOTERICIN B
0.5%
of all AMPHOTERICIN B reports
28
Deaths
26
Hospitalizations
How Dangerous Is Bone marrow failure From AMPHOTERICIN B?
Of the 58 reports, 28 (48.3%) resulted in death, 26 (44.8%) required hospitalization, and 8 (13.8%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMPHOTERICIN B. However, 58 reports have been filed with the FAERS database.
What Other Side Effects Does AMPHOTERICIN B Cause?
Drug ineffective (4,151)
Off label use (1,529)
Condition aggravated (603)
Acute kidney injury (596)
Multiple organ dysfunction syndrome (465)
Pyrexia (388)
Death (379)
Hypokalaemia (353)
Renal impairment (328)
Septic shock (308)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which AMPHOTERICIN B Alternatives Have Lower Bone marrow failure Risk?
AMPHOTERICIN B vs AMPHOTERICIN B\DIMYRISTOYLPHOSPHATIDYLCHOLINE, DL-\DIMYRISTOYLPHOSPHATIDYLGLYCEROL, DL-
AMPHOTERICIN B vs AMPICILLIN
AMPHOTERICIN B vs AMPICILLIN\SULBACTAM
AMPHOTERICIN B vs AMPRENAVIR
AMPHOTERICIN B vs AMPYRA