Does AMPHOTERICIN B Cause Clostridium difficile colitis? 16 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 16 reports of Clostridium difficile colitis have been filed in association with AMPHOTERICIN B (Amphotericin B). This represents 0.2% of all adverse event reports for AMPHOTERICIN B.
16
Reports of Clostridium difficile colitis with AMPHOTERICIN B
0.2%
of all AMPHOTERICIN B reports
8
Deaths
11
Hospitalizations
How Dangerous Is Clostridium difficile colitis From AMPHOTERICIN B?
Of the 16 reports, 8 (50.0%) resulted in death, 11 (68.8%) required hospitalization, and 1 (6.3%) were considered life-threatening.
Is Clostridium difficile colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMPHOTERICIN B. However, 16 reports have been filed with the FAERS database.
What Other Side Effects Does AMPHOTERICIN B Cause?
Drug ineffective (4,151)
Off label use (1,529)
Condition aggravated (603)
Acute kidney injury (596)
Multiple organ dysfunction syndrome (465)
Pyrexia (388)
Death (379)
Hypokalaemia (353)
Renal impairment (328)
Septic shock (308)
What Other Drugs Cause Clostridium difficile colitis?
CYCLOPHOSPHAMIDE (717)
PREDNISONE (619)
DEXAMETHASONE (575)
METHOTREXATE (562)
ETOPOSIDE (503)
CYTARABINE (489)
VINCRISTINE (482)
LENALIDOMIDE (388)
METHYLPREDNISOLONE (385)
CIPROFLOXACIN (378)
Which AMPHOTERICIN B Alternatives Have Lower Clostridium difficile colitis Risk?
AMPHOTERICIN B vs AMPHOTERICIN B\DIMYRISTOYLPHOSPHATIDYLCHOLINE, DL-\DIMYRISTOYLPHOSPHATIDYLGLYCEROL, DL-
AMPHOTERICIN B vs AMPICILLIN
AMPHOTERICIN B vs AMPICILLIN\SULBACTAM
AMPHOTERICIN B vs AMPRENAVIR
AMPHOTERICIN B vs AMPYRA