Does APREMILAST Cause Adrenal insufficiency? 29 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 29 reports of Adrenal insufficiency have been filed in association with APREMILAST (Otezla). This represents 0.0% of all adverse event reports for APREMILAST.
29
Reports of Adrenal insufficiency with APREMILAST
0.0%
of all APREMILAST reports
15
Deaths
25
Hospitalizations
How Dangerous Is Adrenal insufficiency From APREMILAST?
Of the 29 reports, 15 (51.7%) resulted in death, 25 (86.2%) required hospitalization, and 22 (75.9%) were considered life-threatening.
Is Adrenal insufficiency Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 29 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Adrenal insufficiency?
NIVOLUMAB (1,285)
PEMBROLIZUMAB (1,270)
PREDNISONE (1,105)
IPILIMUMAB (851)
METHOTREXATE (644)
ADALIMUMAB (554)
ETANERCEPT (546)
TOCILIZUMAB (541)
HYDROXYCHLOROQUINE (517)
INFLIXIMAB (509)
Which APREMILAST Alternatives Have Lower Adrenal insufficiency Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA