Does APREMILAST Cause Constipation? 548 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 548 reports of Constipation have been filed in association with APREMILAST (Otezla). This represents 0.4% of all adverse event reports for APREMILAST.
548
Reports of Constipation with APREMILAST
0.4%
of all APREMILAST reports
3
Deaths
23
Hospitalizations
How Dangerous Is Constipation From APREMILAST?
Of the 548 reports, 3 (0.5%) resulted in death, 23 (4.2%) required hospitalization, and 1 (0.2%) were considered life-threatening.
Is Constipation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 548 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Constipation?
LENALIDOMIDE (9,635)
NIRAPARIB (4,128)
ADALIMUMAB (4,063)
SEMAGLUTIDE (4,036)
TIRZEPATIDE (3,417)
ERENUMAB-AOOE (3,104)
MORPHINE (2,979)
OXYCODONE (2,747)
PALBOCICLIB (2,705)
POMALIDOMIDE (2,374)
Which APREMILAST Alternatives Have Lower Constipation Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA