Does APREMILAST Cause Musculoskeletal stiffness? 2,314 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,314 reports of Musculoskeletal stiffness have been filed in association with APREMILAST (Otezla). This represents 1.7% of all adverse event reports for APREMILAST.
2,314
Reports of Musculoskeletal stiffness with APREMILAST
1.7%
of all APREMILAST reports
1,167
Deaths
1,256
Hospitalizations
How Dangerous Is Musculoskeletal stiffness From APREMILAST?
Of the 2,314 reports, 1,167 (50.4%) resulted in death, 1,256 (54.3%) required hospitalization, and 1,150 (49.7%) were considered life-threatening.
Is Musculoskeletal stiffness Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 2,314 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Musculoskeletal stiffness?
ADALIMUMAB (10,762)
METHOTREXATE (9,903)
ETANERCEPT (9,744)
TOFACITINIB (7,354)
TOCILIZUMAB (6,346)
RITUXIMAB (6,058)
LEFLUNOMIDE (6,031)
ABATACEPT (5,926)
SECUKINUMAB (5,655)
HYDROXYCHLOROQUINE (5,271)
Which APREMILAST Alternatives Have Lower Musculoskeletal stiffness Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA