Musculoskeletal stiffness: Which Medications Cause It? (67,222 Reports Across 1,367 Drugs)
Boost Your Natural Energy & Metabolism
Mitolyn — 6 exotic plants to unlock your body's fat-burning power. 90-day guarantee.
Musculoskeletal stiffness has been reported as an adverse event with 1,367 different drugs in the FDA's FAERS database, with 67,222 total reports. 2,832 of these reports resulted in death.The drugs most commonly associated with Musculoskeletal stiffness are ADALIMUMAB, METHOTREXATE, and ETANERCEPT.
67,222
Total Reports
1,367
Drugs Involved
2,832
Deaths
14,216
Hospitalizations
55.4 yrs
Average Patient Age
70.2% / 29.8%
Female / Male
Which Drugs Cause Musculoskeletal stiffness Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ADALIMUMAB | 10,762 | 2.2% | 1,508 | 3,294 | 1,810 |
| METHOTREXATE | 9,903 | 3.9% | 1,486 | 3,005 | 1,823 |
| ETANERCEPT | 9,744 | 2.7% | 1,119 | 2,419 | 1,376 |
| TOFACITINIB | 7,354 | 4.7% | 1,205 | 1,985 | 1,493 |
| TOCILIZUMAB | 6,346 | 6.5% | 1,455 | 2,720 | 1,666 |
| RITUXIMAB | 6,058 | 3.4% | 1,525 | 2,754 | 1,824 |
| LEFLUNOMIDE | 6,031 | 10.7% | 1,405 | 2,461 | 1,825 |
| ABATACEPT | 5,926 | 5.1% | 1,238 | 2,356 | 1,685 |
| SECUKINUMAB | 5,655 | 3.7% | 1,421 | 2,116 | 1,801 |
| HYDROXYCHLOROQUINE | 5,271 | 7.9% | 1,297 | 2,260 | 1,596 |
| SULFASALAZINE | 5,154 | 12.8% | 1,284 | 2,200 | 1,583 |
| INFLIXIMAB | 5,065 | 3.6% | 1,332 | 2,267 | 1,661 |
| PREDNISONE | 4,206 | 2.7% | 1,385 | 1,956 | 1,679 |
| CERTOLIZUMAB PEGOL | 4,192 | 4.2% | 1,277 | 1,916 | 1,572 |
| GOLIMUMAB | 3,974 | 5.7% | 1,318 | 1,950 | 1,591 |
| DICLOFENAC | 3,921 | 4.5% | 1,485 | 1,704 | 1,692 |
| ALENDRONATE | 3,210 | 11.5% | 1,358 | 1,882 | 1,676 |
| FOLIC ACID | 3,155 | 13.8% | 1,286 | 1,559 | 1,558 |
| CETIRIZINE | 2,826 | 5.9% | 1,331 | 1,579 | 1,627 |
| ETANERCEPT-SZZS | 2,770 | 23.3% | 1,223 | 1,519 | 1,493 |