Does METHOTREXATE Cause Musculoskeletal stiffness? 9,903 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 9,903 reports of Musculoskeletal stiffness have been filed in association with METHOTREXATE (Methotrexate). This represents 3.9% of all adverse event reports for METHOTREXATE.
9,903
Reports of Musculoskeletal stiffness with METHOTREXATE
3.9%
of all METHOTREXATE reports
1,486
Deaths
3,005
Hospitalizations
How Dangerous Is Musculoskeletal stiffness From METHOTREXATE?
Of the 9,903 reports, 1,486 (15.0%) resulted in death, 3,005 (30.3%) required hospitalization, and 1,823 (18.4%) were considered life-threatening.
Is Musculoskeletal stiffness Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 9,903 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Musculoskeletal stiffness?
ADALIMUMAB (10,762)
ETANERCEPT (9,744)
TOFACITINIB (7,354)
TOCILIZUMAB (6,346)
RITUXIMAB (6,058)
LEFLUNOMIDE (6,031)
ABATACEPT (5,926)
SECUKINUMAB (5,655)
HYDROXYCHLOROQUINE (5,271)
SULFASALAZINE (5,154)
Which METHOTREXATE Alternatives Have Lower Musculoskeletal stiffness Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA