Does APREMILAST Cause Osteoporosis? 622 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 622 reports of Osteoporosis have been filed in association with APREMILAST (Otezla). This represents 0.5% of all adverse event reports for APREMILAST.
622
Reports of Osteoporosis with APREMILAST
0.5%
of all APREMILAST reports
367
Deaths
254
Hospitalizations
How Dangerous Is Osteoporosis From APREMILAST?
Of the 622 reports, 367 (59.0%) resulted in death, 254 (40.8%) required hospitalization, and 246 (39.5%) were considered life-threatening.
Is Osteoporosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 622 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Osteoporosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (7,436)
TENOFOVIR DISOPROXIL (5,302)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,029)
ADALIMUMAB (2,665)
PREDNISONE (2,476)
METHOTREXATE (2,018)
ETANERCEPT (1,766)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (1,720)
TOCILIZUMAB (1,689)
ALENDRONATE (1,688)
Which APREMILAST Alternatives Have Lower Osteoporosis Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA