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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Osteoporosis: Which Medications Cause It? (31,053 Reports Across 900 Drugs)

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Osteoporosis has been reported as an adverse event with 900 different drugs in the FDA's FAERS database, with 31,053 total reports. 1,278 of these reports resulted in death.The drugs most commonly associated with Osteoporosis are EMTRICITABINE\TENOFOVIR DISOPROXIL, TENOFOVIR DISOPROXIL, and EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL.

31,053
Total Reports
900
Drugs Involved
1,278
Deaths
7,999
Hospitalizations
57.3 yrs
Average Patient Age
64.7% / 35.3%
Female / Male

Which Drugs Cause Osteoporosis Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
EMTRICITABINE\TENOFOVIR DISOPROXIL 7,436 18.9% 86 515 0
TENOFOVIR DISOPROXIL 5,302 19.7% 73 370 2
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL 4,029 21.7% 34 283 0
ADALIMUMAB 2,665 0.5% 438 1,258 322
PREDNISONE 2,476 1.6% 404 1,218 414
METHOTREXATE 2,018 0.8% 466 823 360
ETANERCEPT 1,766 0.5% 326 762 233
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL 1,720 20.4% 15 113 0
TOCILIZUMAB 1,689 1.7% 414 813 288
ALENDRONATE 1,688 6.1% 420 1,199 343
ABATACEPT 1,467 1.3% 377 754 294
LEFLUNOMIDE 1,430 2.5% 313 717 316
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL 1,415 19.6% 14 78 0
TOFACITINIB 1,395 0.9% 300 673 215
RITUXIMAB 1,386 0.8% 397 682 422
HYDROXYCHLOROQUINE 1,152 1.7% 366 665 275
SULFASALAZINE 996 2.5% 382 389 282
CERTOLIZUMAB PEGOL 876 0.9% 375 311 263
GOLIMUMAB 867 1.3% 364 316 250
INFLIXIMAB 829 0.6% 357 407 258

View all 900 drugs →

Top 3 Drugs Associated With Osteoporosis

5,302 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)