Does LEFLUNOMIDE Cause Osteoporosis? 1,430 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,430 reports of Osteoporosis have been filed in association with LEFLUNOMIDE (Leflunomide). This represents 2.5% of all adverse event reports for LEFLUNOMIDE.
1,430
Reports of Osteoporosis with LEFLUNOMIDE
2.5%
of all LEFLUNOMIDE reports
313
Deaths
717
Hospitalizations
How Dangerous Is Osteoporosis From LEFLUNOMIDE?
Of the 1,430 reports, 313 (21.9%) resulted in death, 717 (50.1%) required hospitalization, and 316 (22.1%) were considered life-threatening.
Is Osteoporosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEFLUNOMIDE. However, 1,430 reports have been filed with the FAERS database.
What Other Side Effects Does LEFLUNOMIDE Cause?
Drug ineffective (31,396)
Rheumatoid arthritis (20,886)
Pain (15,594)
Drug intolerance (14,142)
Joint swelling (13,026)
Fatigue (11,959)
Arthralgia (11,880)
Rash (11,239)
Contraindicated product administered (11,206)
Abdominal discomfort (10,333)
What Other Drugs Cause Osteoporosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (7,436)
TENOFOVIR DISOPROXIL (5,302)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,029)
ADALIMUMAB (2,665)
PREDNISONE (2,476)
METHOTREXATE (2,018)
ETANERCEPT (1,766)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (1,720)
TOCILIZUMAB (1,689)
ALENDRONATE (1,688)
Which LEFLUNOMIDE Alternatives Have Lower Osteoporosis Risk?
LEFLUNOMIDE vs LEMBOREXANT
LEFLUNOMIDE vs LENACAPAVIR
LEFLUNOMIDE vs LENALIDOMIDE
LEFLUNOMIDE vs LENIOLISIB
LEFLUNOMIDE vs LENOGRASTIM