Does TOFACITINIB Cause Osteoporosis? 1,395 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,395 reports of Osteoporosis have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.9% of all adverse event reports for TOFACITINIB.
1,395
Reports of Osteoporosis with TOFACITINIB
0.9%
of all TOFACITINIB reports
300
Deaths
673
Hospitalizations
How Dangerous Is Osteoporosis From TOFACITINIB?
Of the 1,395 reports, 300 (21.5%) resulted in death, 673 (48.2%) required hospitalization, and 215 (15.4%) were considered life-threatening.
Is Osteoporosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 1,395 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Osteoporosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (7,436)
TENOFOVIR DISOPROXIL (5,302)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,029)
ADALIMUMAB (2,665)
PREDNISONE (2,476)
METHOTREXATE (2,018)
ETANERCEPT (1,766)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (1,720)
TOCILIZUMAB (1,689)
ALENDRONATE (1,688)
Which TOFACITINIB Alternatives Have Lower Osteoporosis Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN