Does APREMILAST Cause Synovitis? 2,424 Reports in FDA Database

Q: Does APREMILAST cause Synovitis?

2,424 reports of Synovitis have been filed with the FDA for APREMILAST, representing 1.8% of all APREMILAST adverse event reports.

Q: How dangerous is Synovitis from APREMILAST?

Of 2,424 reports, 1,585 (65.4%) resulted in death and 1,631 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 2,424 reports of Synovitis have been filed in association with APREMILAST (Otezla). This represents 1.8% of all adverse event reports for APREMILAST.

2,424

Reports of Synovitis with APREMILAST

1.8%

of all APREMILAST reports

1,585

Deaths

1,631

Hospitalizations

How Dangerous Is Synovitis From APREMILAST?

Of the 2,424 reports, 1,585 (65.4%) resulted in death, 1,631 (67.3%) required hospitalization, and 1,472 (60.7%) were considered life-threatening.

Is Synovitis Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 2,424 reports have been filed with the FAERS database.

What Other Side Effects Does APREMILAST Cause?

Diarrhoea (23,752) Nausea (21,352) Psoriasis (19,255) Headache (17,024) Drug ineffective (14,121) Abdominal discomfort (7,653) Psoriatic arthropathy (7,035) Vomiting (5,959) Rash (5,883) Pain (5,676)

What Other Drugs Cause Synovitis?

METHOTREXATE (11,451) ADALIMUMAB (9,965) ABATACEPT (9,783) ETANERCEPT (9,599) TOCILIZUMAB (9,428) HYDROXYCHLOROQUINE (9,123) LEFLUNOMIDE (8,889) RITUXIMAB (7,956) INFLIXIMAB (7,856) SULFASALAZINE (7,566)

Which APREMILAST Alternatives Have Lower Synovitis Risk?

APREMILAST vs APREPITANT APREMILAST vs APROTININ APREMILAST vs ARANESP APREMILAST vs ARAVA APREMILAST vs AREDIA

APREMILAST Full Profile All Synovitis Reports All Drugs Causing Synovitis APREMILAST Demographics