Does SULFASALAZINE Cause Synovitis? 7,566 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 7,566 reports of Synovitis have been filed in association with SULFASALAZINE (Azulfidine EN-tabs). This represents 18.8% of all adverse event reports for SULFASALAZINE.
7,566
Reports of Synovitis with SULFASALAZINE
18.8%
of all SULFASALAZINE reports
1,738
Deaths
2,992
Hospitalizations
How Dangerous Is Synovitis From SULFASALAZINE?
Of the 7,566 reports, 1,738 (23.0%) resulted in death, 2,992 (39.5%) required hospitalization, and 2,075 (27.4%) were considered life-threatening.
Is Synovitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SULFASALAZINE. However, 7,566 reports have been filed with the FAERS database.
What Other Side Effects Does SULFASALAZINE Cause?
Drug ineffective (22,365)
Rheumatoid arthritis (15,136)
Drug intolerance (11,530)
Pain (11,309)
Fatigue (9,684)
Joint swelling (9,673)
Rash (8,739)
Contraindicated product administered (8,698)
Arthralgia (8,527)
Abdominal discomfort (8,404)
What Other Drugs Cause Synovitis?
METHOTREXATE (11,451)
ADALIMUMAB (9,965)
ABATACEPT (9,783)
ETANERCEPT (9,599)
TOCILIZUMAB (9,428)
HYDROXYCHLOROQUINE (9,123)
LEFLUNOMIDE (8,889)
RITUXIMAB (7,956)
INFLIXIMAB (7,856)
TOFACITINIB (7,272)
Which SULFASALAZINE Alternatives Have Lower Synovitis Risk?
SULFASALAZINE vs SULFATHIAZOLE
SULFASALAZINE vs SULFISOMIDINE
SULFASALAZINE vs SULFUR
SULFASALAZINE vs SULFUR HEXAFLUORIDE
SULFASALAZINE vs SULINDAC