Does TOFACITINIB Cause Synovitis? 7,272 Reports in FDA Database

Q: Does TOFACITINIB cause Synovitis?

7,272 reports of Synovitis have been filed with the FDA for TOFACITINIB, representing 4.7% of all TOFACITINIB adverse event reports.

Q: How dangerous is Synovitis from TOFACITINIB?

Of 7,272 reports, 1,628 (22.4%) resulted in death and 2,662 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 7,272 reports of Synovitis have been filed in association with TOFACITINIB (XELJANZ XR). This represents 4.7% of all adverse event reports for TOFACITINIB.

7,272

Reports of Synovitis with TOFACITINIB

4.7%

of all TOFACITINIB reports

1,628

Deaths

2,662

Hospitalizations

How Dangerous Is Synovitis From TOFACITINIB?

Of the 7,272 reports, 1,628 (22.4%) resulted in death, 2,662 (36.6%) required hospitalization, and 1,953 (26.9%) were considered life-threatening.

Is Synovitis Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 7,272 reports have been filed with the FAERS database.

What Other Side Effects Does TOFACITINIB Cause?

Drug ineffective (30,382) Pain (21,659) Condition aggravated (16,925) Arthralgia (15,640) Fatigue (13,551) Rheumatoid arthritis (12,277) Off label use (11,736) Headache (11,061) Joint swelling (10,686) Malaise (9,040)

What Other Drugs Cause Synovitis?

METHOTREXATE (11,451) ADALIMUMAB (9,965) ABATACEPT (9,783) ETANERCEPT (9,599) TOCILIZUMAB (9,428) HYDROXYCHLOROQUINE (9,123) LEFLUNOMIDE (8,889) RITUXIMAB (7,956) INFLIXIMAB (7,856) SULFASALAZINE (7,566)

Which TOFACITINIB Alternatives Have Lower Synovitis Risk?

TOFACITINIB vs TOFERSEN TOFACITINIB vs TOLNAFTATE TOFACITINIB vs TOLODODEKIN ALFA TOFACITINIB vs TOLTERODINE TOFACITINIB vs TOLVAPTAN

TOFACITINIB Full Profile All Synovitis Reports All Drugs Causing Synovitis TOFACITINIB Demographics