Does ATOVAQUONE Cause Cholestasis? 51 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 51 reports of Cholestasis have been filed in association with ATOVAQUONE (Atovaquone). This represents 2.2% of all adverse event reports for ATOVAQUONE.
51
Reports of Cholestasis with ATOVAQUONE
2.2%
of all ATOVAQUONE reports
2
Deaths
34
Hospitalizations
How Dangerous Is Cholestasis From ATOVAQUONE?
Of the 51 reports, 2 (3.9%) resulted in death, 34 (66.7%) required hospitalization.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ATOVAQUONE. However, 51 reports have been filed with the FAERS database.
What Other Side Effects Does ATOVAQUONE Cause?
Off label use (176)
Drug ineffective (164)
Condition aggravated (145)
Thrombocytopenia (127)
Pyrexia (117)
Rash (108)
Neutropenia (89)
Diarrhoea (86)
Pneumocystis jirovecii pneumonia (83)
Product use in unapproved indication (83)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which ATOVAQUONE Alternatives Have Lower Cholestasis Risk?
ATOVAQUONE vs ATOVAQUONE\PROGUANIL
ATOVAQUONE vs ATRACURIUM
ATOVAQUONE vs ATRIPLA
ATOVAQUONE vs ATROPINE
ATOVAQUONE vs ATROPINE\ATROPINE