Does AZELAIC ACID Cause Synovitis? 162 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 162 reports of Synovitis have been filed in association with AZELAIC ACID (azelaic acid). This represents 13.5% of all adverse event reports for AZELAIC ACID.
162
Reports of Synovitis with AZELAIC ACID
13.5%
of all AZELAIC ACID reports
160
Deaths
94
Hospitalizations
How Dangerous Is Synovitis From AZELAIC ACID?
Of the 162 reports, 160 (98.8%) resulted in death, 94 (58.0%) required hospitalization, and 96 (59.3%) were considered life-threatening.
Is Synovitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AZELAIC ACID. However, 162 reports have been filed with the FAERS database.
What Other Side Effects Does AZELAIC ACID Cause?
Drug ineffective (344)
Hypoaesthesia (311)
Gastrooesophageal reflux disease (308)
Abdominal pain upper (300)
Paraesthesia (300)
Blepharospasm (298)
Epilepsy (294)
Drug intolerance (286)
Taste disorder (286)
Product use in unapproved indication (271)
What Other Drugs Cause Synovitis?
METHOTREXATE (11,451)
ADALIMUMAB (9,965)
ABATACEPT (9,783)
ETANERCEPT (9,599)
TOCILIZUMAB (9,428)
HYDROXYCHLOROQUINE (9,123)
LEFLUNOMIDE (8,889)
RITUXIMAB (7,956)
INFLIXIMAB (7,856)
SULFASALAZINE (7,566)
Which AZELAIC ACID Alternatives Have Lower Synovitis Risk?
AZELAIC ACID vs AZELASTINE
AZELAIC ACID vs AZELASTINE\FLUTICASONE
AZELAIC ACID vs AZELNIDIPINE
AZELAIC ACID vs AZILECT
AZELAIC ACID vs AZILSARTAN KAMEDOXOMIL