Does BENZOCAINE Cause Synovitis? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Synovitis have been filed in association with BENZOCAINE (ANAL-ESE). This represents 1.8% of all adverse event reports for BENZOCAINE.
10
Reports of Synovitis with BENZOCAINE
1.8%
of all BENZOCAINE reports
8
Deaths
10
Hospitalizations
How Dangerous Is Synovitis From BENZOCAINE?
Of the 10 reports, 8 (80.0%) resulted in death, 10 (100.0%) required hospitalization, and 10 (100.0%) were considered life-threatening.
Is Synovitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BENZOCAINE. However, 10 reports have been filed with the FAERS database.
What Other Side Effects Does BENZOCAINE Cause?
Methaemoglobinaemia (162)
Drug hypersensitivity (57)
Dyspnoea (53)
Off label use (53)
Drug ineffective (49)
Condition aggravated (37)
Maternal exposure during pregnancy (36)
Asthma (32)
Cyanosis (32)
Asthenia (30)
What Other Drugs Cause Synovitis?
METHOTREXATE (11,451)
ADALIMUMAB (9,965)
ABATACEPT (9,783)
ETANERCEPT (9,599)
TOCILIZUMAB (9,428)
HYDROXYCHLOROQUINE (9,123)
LEFLUNOMIDE (8,889)
RITUXIMAB (7,956)
INFLIXIMAB (7,856)
SULFASALAZINE (7,566)
Which BENZOCAINE Alternatives Have Lower Synovitis Risk?
BENZOCAINE vs BENZODIAZEPINE
BENZOCAINE vs BENZONATATE
BENZOCAINE vs BENZOYL PEROXIDE
BENZOCAINE vs BENZOYL PEROXIDE\CLINDAMYCIN
BENZOCAINE vs BENZOYLECGONINE