Does BEVACIZUMAB Cause Cholestasis? 165 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 165 reports of Cholestasis have been filed in association with BEVACIZUMAB (JOBEVNE). This represents 0.2% of all adverse event reports for BEVACIZUMAB.
165
Reports of Cholestasis with BEVACIZUMAB
0.2%
of all BEVACIZUMAB reports
31
Deaths
69
Hospitalizations
How Dangerous Is Cholestasis From BEVACIZUMAB?
Of the 165 reports, 31 (18.8%) resulted in death, 69 (41.8%) required hospitalization, and 3 (1.8%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BEVACIZUMAB. However, 165 reports have been filed with the FAERS database.
What Other Side Effects Does BEVACIZUMAB Cause?
Off label use (12,094)
Death (8,493)
Diarrhoea (4,911)
Disease progression (4,653)
Fatigue (4,572)
Nausea (4,357)
Hypertension (4,309)
Anaemia (3,221)
Vomiting (3,193)
Neutropenia (2,875)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which BEVACIZUMAB Alternatives Have Lower Cholestasis Risk?
BEVACIZUMAB vs BEVACIZUMAB-AWWB
BEVACIZUMAB vs BEVACIZUMAB-BVZR
BEVACIZUMAB vs BEVACIZUMAB-MALY
BEVACIZUMAB vs BEXAROTENE
BEVACIZUMAB vs BEYAZ