Does BINIMETINIB Cause Pancytopenia? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Pancytopenia have been filed in association with BINIMETINIB (MEKTOVI). This represents 0.1% of all adverse event reports for BINIMETINIB.
10
Reports of Pancytopenia with BINIMETINIB
0.1%
of all BINIMETINIB reports
1
Deaths
8
Hospitalizations
How Dangerous Is Pancytopenia From BINIMETINIB?
Of the 10 reports, 1 (10.0%) resulted in death, 8 (80.0%) required hospitalization, and 3 (30.0%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BINIMETINIB. However, 10 reports have been filed with the FAERS database.
What Other Side Effects Does BINIMETINIB Cause?
Off label use (902)
Death (719)
Nausea (657)
Fatigue (562)
Diarrhoea (521)
Product use in unapproved indication (508)
Pyrexia (490)
Neoplasm progression (387)
Vomiting (375)
Rash (360)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which BINIMETINIB Alternatives Have Lower Pancytopenia Risk?
BINIMETINIB vs BIOFLAVONOIDS
BINIMETINIB vs BIOTIN
BINIMETINIB vs BIPERIDEN
BINIMETINIB vs BIRCH TRITERPENES
BINIMETINIB vs BISACODYL