BORTEZOMIB for C3 glomerulopathy: Side Effects & Safety Data
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There are 28 adverse event reports in the FDA FAERS database where BORTEZOMIB was used for C3 glomerulopathy.
Most Reported Side Effects for BORTEZOMIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Plasma cell myeloma | 6,683 | 14.0% | 1,185 | 694 |
| Off label use | 4,754 | 10.0% | 956 | 1,101 |
| Neuropathy peripheral | 4,067 | 8.5% | 226 | 488 |
| Drug ineffective | 2,730 | 5.7% | 565 | 532 |
| Diarrhoea | 2,244 | 4.7% | 296 | 944 |
| Thrombocytopenia | 2,082 | 4.4% | 391 | 716 |
| Death | 2,025 | 4.2% | 2,018 | 251 |
| Pneumonia | 2,020 | 4.2% | 519 | 1,308 |
| Fatigue | 1,757 | 3.7% | 188 | 446 |
| Neutropenia | 1,530 | 3.2% | 247 | 428 |
| Anaemia | 1,486 | 3.1% | 306 | 593 |
| Disease progression | 1,399 | 2.9% | 355 | 233 |
| Pyrexia | 1,384 | 2.9% | 204 | 854 |
| Intentional product use issue | 1,361 | 2.9% | 250 | 126 |
| Nausea | 1,318 | 2.8% | 160 | 501 |
Other Indications for BORTEZOMIB
Plasma cell myeloma (31,567)
Product used for unknown indication (6,690)
Amyloidosis (1,044)
Primary amyloidosis (905)
Plasma cell myeloma refractory (848)
Mantle cell lymphoma (630)
Plasma cell leukaemia (458)
Waldenstrom's macroglobulinaemia (425)
Chemotherapy (298)
Plasmablastic lymphoma (216)
Other Drugs Used for C3 glomerulopathy
ECULIZUMAB (267)
MYCOPHENOLATE MOFETIL (126)
RAVULIZUMAB-CWVZ (59)
PREDNISONE (46)
PREDNISOLONE (45)
RITUXIMAB (34)
PEGCETACOPLAN (27)
DEXAMETHASONE (24)
TACROLIMUS (23)
IPTACOPAN (21)