RAVULIZUMAB-CWVZ for C3 glomerulopathy: Side Effects & Safety Data
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There are 59 adverse event reports in the FDA FAERS database where RAVULIZUMAB-CWVZ was used for C3 glomerulopathy.
Most Reported Side Effects for RAVULIZUMAB-CWVZ
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Fatigue | 1,472 | 14.4% | 2 | 127 |
| Asthenia | 727 | 7.1% | 1 | 94 |
| Headache | 639 | 6.3% | 3 | 73 |
| Drug ineffective | 570 | 5.6% | 6 | 73 |
| Off label use | 451 | 4.4% | 9 | 44 |
| Muscular weakness | 422 | 4.1% | 2 | 38 |
| Dyspnoea | 414 | 4.1% | 5 | 89 |
| Malaise | 353 | 3.5% | 3 | 53 |
| Haemoglobin decreased | 346 | 3.4% | 6 | 70 |
| Myasthenia gravis | 338 | 3.3% | 8 | 139 |
| Back pain | 326 | 3.2% | 1 | 35 |
| Pain | 318 | 3.1% | 0 | 50 |
| Therapeutic response shortened | 316 | 3.1% | 1 | 30 |
| Death | 313 | 3.1% | 313 | 9 |
| Feeling abnormal | 307 | 3.0% | 1 | 24 |
Other Indications for RAVULIZUMAB-CWVZ
Myasthenia gravis (3,781)
Paroxysmal nocturnal haemoglobinuria (2,175)
Product used for unknown indication (1,815)
Atypical haemolytic uraemic syndrome (1,121)
Neuromyelitis optica spectrum disorder (403)
Off label use (259)
Haemolytic uraemic syndrome (93)
Thrombotic microangiopathy (62)
Renal transplant (11)
Renal disorder (10)
Other Drugs Used for C3 glomerulopathy
ECULIZUMAB (267)
MYCOPHENOLATE MOFETIL (126)
PREDNISONE (46)
PREDNISOLONE (45)
RITUXIMAB (34)
BORTEZOMIB (28)
PEGCETACOPLAN (27)
DEXAMETHASONE (24)
TACROLIMUS (23)
IPTACOPAN (21)