RAVULIZUMAB-CWVZ for Off label use: Side Effects & Safety Data
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There are 259 adverse event reports in the FDA FAERS database where RAVULIZUMAB-CWVZ was used for Off label use.
Most Reported Side Effects for RAVULIZUMAB-CWVZ
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Fatigue | 1,472 | 14.4% | 2 | 127 |
| Asthenia | 727 | 7.1% | 1 | 94 |
| Headache | 639 | 6.3% | 3 | 73 |
| Drug ineffective | 570 | 5.6% | 6 | 73 |
| Off label use | 451 | 4.4% | 9 | 44 |
| Muscular weakness | 422 | 4.1% | 2 | 38 |
| Dyspnoea | 414 | 4.1% | 5 | 89 |
| Malaise | 353 | 3.5% | 3 | 53 |
| Haemoglobin decreased | 346 | 3.4% | 6 | 70 |
| Myasthenia gravis | 338 | 3.3% | 8 | 139 |
| Back pain | 326 | 3.2% | 1 | 35 |
| Pain | 318 | 3.1% | 0 | 50 |
| Therapeutic response shortened | 316 | 3.1% | 1 | 30 |
| Death | 313 | 3.1% | 313 | 9 |
| Feeling abnormal | 307 | 3.0% | 1 | 24 |
Other Indications for RAVULIZUMAB-CWVZ
Myasthenia gravis (3,781)
Paroxysmal nocturnal haemoglobinuria (2,175)
Product used for unknown indication (1,815)
Atypical haemolytic uraemic syndrome (1,121)
Neuromyelitis optica spectrum disorder (403)
Haemolytic uraemic syndrome (93)
Thrombotic microangiopathy (62)
C3 glomerulopathy (59)
Renal transplant (11)
Renal disorder (10)
Other Drugs Used for Off label use
LENALIDOMIDE (5,767)
ECULIZUMAB (3,550)
CERTOLIZUMAB PEGOL (2,256)
ABOBOTULINUMTOXINA (2,170)
LEVETIRACETAM (2,161)
APREMILAST (1,995)
PROPRANOLOL (1,576)
CETIRIZINE (1,416)
HUMAN IMMUNOGLOBULIN G (1,129)
THALIDOMIDE (1,033)