Does BRIGATINIB Cause Cholestasis? 8 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 8 reports of Cholestasis have been filed in association with BRIGATINIB (Alunbrig). This represents 0.2% of all adverse event reports for BRIGATINIB.
8
Reports of Cholestasis with BRIGATINIB
0.2%
of all BRIGATINIB reports
0
Deaths
6
Hospitalizations
How Dangerous Is Cholestasis From BRIGATINIB?
Of the 8 reports, 6 (75.0%) required hospitalization.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BRIGATINIB. However, 8 reports have been filed with the FAERS database.
What Other Side Effects Does BRIGATINIB Cause?
Death (405)
Non-small cell lung cancer (370)
Off label use (256)
Diarrhoea (239)
Metastases to central nervous system (219)
Nausea (218)
Lung neoplasm malignant (216)
Fatigue (201)
Blood creatine phosphokinase increased (198)
Product dose omission issue (193)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which BRIGATINIB Alternatives Have Lower Cholestasis Risk?
BRIGATINIB vs BRILINTA
BRIGATINIB vs BRILIQUE
BRIGATINIB vs BRIMONIDINE
BRIGATINIB vs BRIMONIDINE\BRINZOLAMIDE
BRIGATINIB vs BRIMONIDINE\TIMOLOL