Does BRIGATINIB Cause Renal impairment? 54 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 54 reports of Renal impairment have been filed in association with BRIGATINIB (Alunbrig). This represents 1.6% of all adverse event reports for BRIGATINIB.
54
Reports of Renal impairment with BRIGATINIB
1.6%
of all BRIGATINIB reports
5
Deaths
9
Hospitalizations
How Dangerous Is Renal impairment From BRIGATINIB?
Of the 54 reports, 5 (9.3%) resulted in death, 9 (16.7%) required hospitalization, and 2 (3.7%) were considered life-threatening.
Is Renal impairment Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BRIGATINIB. However, 54 reports have been filed with the FAERS database.
What Other Side Effects Does BRIGATINIB Cause?
Death (405)
Non-small cell lung cancer (370)
Off label use (256)
Diarrhoea (239)
Metastases to central nervous system (219)
Nausea (218)
Lung neoplasm malignant (216)
Fatigue (201)
Blood creatine phosphokinase increased (198)
Product dose omission issue (193)
What Other Drugs Cause Renal impairment?
LENALIDOMIDE (2,161)
EMTRICITABINE\TENOFOVIR DISOPROXIL (2,128)
TACROLIMUS (2,124)
OMEPRAZOLE (2,075)
LANSOPRAZOLE (2,063)
METHOTREXATE (1,852)
ESOMEPRAZOLE (1,811)
PANTOPRAZOLE (1,713)
SACUBITRIL\VALSARTAN (1,610)
CYCLOSPORINE (1,489)
Which BRIGATINIB Alternatives Have Lower Renal impairment Risk?
BRIGATINIB vs BRILINTA
BRIGATINIB vs BRILIQUE
BRIGATINIB vs BRIMONIDINE
BRIGATINIB vs BRIMONIDINE\BRINZOLAMIDE
BRIGATINIB vs BRIMONIDINE\TIMOLOL