Does METHOTREXATE Cause Renal impairment? 1,852 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,852 reports of Renal impairment have been filed in association with METHOTREXATE (Methotrexate). This represents 0.7% of all adverse event reports for METHOTREXATE.
1,852
Reports of Renal impairment with METHOTREXATE
0.7%
of all METHOTREXATE reports
181
Deaths
719
Hospitalizations
How Dangerous Is Renal impairment From METHOTREXATE?
Of the 1,852 reports, 181 (9.8%) resulted in death, 719 (38.8%) required hospitalization, and 128 (6.9%) were considered life-threatening.
Is Renal impairment Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 1,852 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Renal impairment?
LENALIDOMIDE (2,161)
EMTRICITABINE\TENOFOVIR DISOPROXIL (2,128)
TACROLIMUS (2,124)
OMEPRAZOLE (2,075)
LANSOPRAZOLE (2,063)
ESOMEPRAZOLE (1,811)
PANTOPRAZOLE (1,713)
SACUBITRIL\VALSARTAN (1,610)
CYCLOSPORINE (1,489)
APIXABAN (1,456)
Which METHOTREXATE Alternatives Have Lower Renal impairment Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA