Renal impairment: Which Medications Cause It? (62,650 Reports Across 1,327 Drugs)
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Renal impairment has been reported as an adverse event with 1,327 different drugs in the FDA's FAERS database, with 62,650 total reports. 5,869 of these reports resulted in death.The drugs most commonly associated with Renal impairment are LENALIDOMIDE, EMTRICITABINE\TENOFOVIR DISOPROXIL, and TACROLIMUS.
62,650
Total Reports
1,327
Drugs Involved
5,869
Deaths
23,652
Hospitalizations
62.4 yrs
Average Patient Age
48.3% / 51.7%
Female / Male
Which Drugs Cause Renal impairment Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| LENALIDOMIDE | 2,161 | 0.6% | 207 | 689 | 65 |
| EMTRICITABINE\TENOFOVIR DISOPROXIL | 2,128 | 5.4% | 45 | 254 | 15 |
| TACROLIMUS | 2,124 | 2.3% | 338 | 1,173 | 285 |
| OMEPRAZOLE | 2,075 | 2.4% | 266 | 444 | 90 |
| LANSOPRAZOLE | 2,063 | 3.4% | 264 | 357 | 56 |
| METHOTREXATE | 1,852 | 0.7% | 181 | 719 | 128 |
| ESOMEPRAZOLE | 1,811 | 2.4% | 227 | 325 | 33 |
| PANTOPRAZOLE | 1,713 | 2.2% | 221 | 384 | 25 |
| SACUBITRIL\VALSARTAN | 1,610 | 1.5% | 138 | 523 | 42 |
| CYCLOSPORINE | 1,489 | 2.2% | 169 | 464 | 78 |
| APIXABAN | 1,456 | 0.9% | 80 | 521 | 36 |
| PEMBROLIZUMAB | 1,447 | 1.7% | 132 | 551 | 88 |
| TENOFOVIR DISOPROXIL | 1,435 | 5.3% | 28 | 203 | 0 |
| METFORMIN | 1,423 | 1.6% | 82 | 780 | 226 |
| MYCOPHENOLATE MOFETIL | 1,390 | 1.9% | 214 | 652 | 165 |
| RITUXIMAB | 1,324 | 0.7% | 177 | 448 | 82 |
| ADALIMUMAB | 1,223 | 0.2% | 60 | 558 | 10 |
| FUROSEMIDE | 1,211 | 2.3% | 127 | 667 | 103 |
| PREDNISOLONE | 1,140 | 1.4% | 182 | 615 | 116 |
| EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL | 1,124 | 6.1% | 20 | 135 | 0 |
Top 3 Drugs Associated With Renal impairment
2,161 reports
2,128 reports
2,124 reports