Does BUPIVACAINE Cause Cholestasis? 7 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 7 reports of Cholestasis have been filed in association with BUPIVACAINE (Bupivacaine Hydrochloride). This represents 0.1% of all adverse event reports for BUPIVACAINE.
7
Reports of Cholestasis with BUPIVACAINE
0.1%
of all BUPIVACAINE reports
0
Deaths
6
Hospitalizations
How Dangerous Is Cholestasis From BUPIVACAINE?
Of the 7 reports, 6 (85.7%) required hospitalization.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUPIVACAINE. However, 7 reports have been filed with the FAERS database.
What Other Side Effects Does BUPIVACAINE Cause?
Drug ineffective (3,068)
Off label use (912)
Pain (746)
Anaesthetic complication (585)
Maternal exposure during pregnancy (491)
Hypotension (460)
Hypoaesthesia (455)
Exposure during pregnancy (391)
Nausea (328)
Drug withdrawal syndrome (280)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which BUPIVACAINE Alternatives Have Lower Cholestasis Risk?
BUPIVACAINE vs BUPIVACAINE\BUPIVACAINE ANHYDROUS
BUPIVACAINE vs BUPIVACAINE\EPINEPHRINE
BUPIVACAINE vs BUPIVACAINE\MELOXICAM
BUPIVACAINE vs BUPRENORPHINE
BUPIVACAINE vs BUPRENORPHINE\NALOXONE