Does BUPIVACAINE Cause Hepatitis? 13 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Hepatitis have been filed in association with BUPIVACAINE (Bupivacaine Hydrochloride). This represents 0.1% of all adverse event reports for BUPIVACAINE.
13
Reports of Hepatitis with BUPIVACAINE
0.1%
of all BUPIVACAINE reports
1
Deaths
6
Hospitalizations
How Dangerous Is Hepatitis From BUPIVACAINE?
Of the 13 reports, 1 (7.7%) resulted in death, 6 (46.2%) required hospitalization, and 1 (7.7%) were considered life-threatening.
Is Hepatitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUPIVACAINE. However, 13 reports have been filed with the FAERS database.
What Other Side Effects Does BUPIVACAINE Cause?
Drug ineffective (3,068)
Off label use (912)
Pain (746)
Anaesthetic complication (585)
Maternal exposure during pregnancy (491)
Hypotension (460)
Hypoaesthesia (455)
Exposure during pregnancy (391)
Nausea (328)
Drug withdrawal syndrome (280)
What Other Drugs Cause Hepatitis?
METHOTREXATE (1,835)
ACETAMINOPHEN (1,450)
TOCILIZUMAB (1,184)
HYDROXYCHLOROQUINE (1,133)
ADALIMUMAB (1,096)
RITUXIMAB (1,017)
ETANERCEPT (1,013)
LEFLUNOMIDE (997)
PEMBROLIZUMAB (935)
NIVOLUMAB (930)
Which BUPIVACAINE Alternatives Have Lower Hepatitis Risk?
BUPIVACAINE vs BUPIVACAINE\BUPIVACAINE ANHYDROUS
BUPIVACAINE vs BUPIVACAINE\EPINEPHRINE
BUPIVACAINE vs BUPIVACAINE\MELOXICAM
BUPIVACAINE vs BUPRENORPHINE
BUPIVACAINE vs BUPRENORPHINE\NALOXONE