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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Hepatitis: Which Medications Cause It? (16,371 Reports Across 852 Drugs)

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Hepatitis has been reported as an adverse event with 852 different drugs in the FDA's FAERS database, with 16,371 total reports. 1,979 of these reports resulted in death.The drugs most commonly associated with Hepatitis are METHOTREXATE, ACETAMINOPHEN, and TOCILIZUMAB.

16,371
Total Reports
852
Drugs Involved
1,979
Deaths
7,618
Hospitalizations
53.5 yrs
Average Patient Age
60.0% / 40.0%
Female / Male

Which Drugs Cause Hepatitis Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
METHOTREXATE 1,835 0.7% 425 736 414
ACETAMINOPHEN 1,450 1.1% 436 1,096 481
TOCILIZUMAB 1,184 1.2% 364 631 335
HYDROXYCHLOROQUINE 1,133 1.7% 301 580 306
ADALIMUMAB 1,096 0.2% 402 620 408
RITUXIMAB 1,017 0.6% 484 697 423
ETANERCEPT 1,013 0.3% 311 467 317
LEFLUNOMIDE 997 1.8% 418 587 429
PEMBROLIZUMAB 935 1.1% 167 431 79
NIVOLUMAB 930 1.1% 179 447 106
ABATACEPT 902 0.8% 263 466 309
PREDNISONE 866 0.6% 372 510 337
INFLIXIMAB 785 0.6% 304 514 313
SULFASALAZINE 754 1.9% 299 468 315
AZATHIOPRINE 705 2.1% 331 476 345
SECUKINUMAB 596 0.4% 400 481 395
CERTOLIZUMAB PEGOL 584 0.6% 315 428 332
IPILIMUMAB 571 1.6% 88 288 62
METHYLPREDNISOLONE 547 0.9% 338 414 309
GOLIMUMAB 544 0.8% 300 399 299

View all 852 drugs →

Top 3 Drugs Associated With Hepatitis

1,835 reports
1,450 reports
1,184 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)