Does BUPIVACAINE Cause Pruritus? 133 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 133 reports of Pruritus have been filed in association with BUPIVACAINE (Bupivacaine Hydrochloride). This represents 1.2% of all adverse event reports for BUPIVACAINE.
133
Reports of Pruritus with BUPIVACAINE
1.2%
of all BUPIVACAINE reports
36
Deaths
59
Hospitalizations
How Dangerous Is Pruritus From BUPIVACAINE?
Of the 133 reports, 36 (27.1%) resulted in death, 59 (44.4%) required hospitalization, and 46 (34.6%) were considered life-threatening.
Is Pruritus Listed in the Official Label?
Yes, Pruritus is listed as a known adverse reaction in the official FDA drug label for BUPIVACAINE.
What Other Side Effects Does BUPIVACAINE Cause?
Drug ineffective (3,068)
Off label use (912)
Pain (746)
Anaesthetic complication (585)
Maternal exposure during pregnancy (491)
Hypotension (460)
Hypoaesthesia (455)
Exposure during pregnancy (391)
Nausea (328)
Drug withdrawal syndrome (280)
What Other Drugs Cause Pruritus?
DUPILUMAB (44,279)
ADAPALENE (12,072)
ADALIMUMAB (9,644)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (9,439)
SECUKINUMAB (8,755)
ETANERCEPT (8,047)
METHOTREXATE (7,526)
LENALIDOMIDE (6,304)
TOCILIZUMAB (5,973)
RITUXIMAB (5,548)
Which BUPIVACAINE Alternatives Have Lower Pruritus Risk?
BUPIVACAINE vs BUPIVACAINE\BUPIVACAINE ANHYDROUS
BUPIVACAINE vs BUPIVACAINE\EPINEPHRINE
BUPIVACAINE vs BUPIVACAINE\MELOXICAM
BUPIVACAINE vs BUPRENORPHINE
BUPIVACAINE vs BUPRENORPHINE\NALOXONE