Does BUPRENORPHINE Cause Malaise? 1,133 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,133 reports of Malaise have been filed in association with BUPRENORPHINE (Buprenorphine and Naloxone). This represents 1.4% of all adverse event reports for BUPRENORPHINE.
1,133
Reports of Malaise with BUPRENORPHINE
1.4%
of all BUPRENORPHINE reports
479
Deaths
416
Hospitalizations
How Dangerous Is Malaise From BUPRENORPHINE?
Of the 1,133 reports, 479 (42.3%) resulted in death, 416 (36.7%) required hospitalization, and 346 (30.5%) were considered life-threatening.
Is Malaise Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUPRENORPHINE. However, 1,133 reports have been filed with the FAERS database.
What Other Side Effects Does BUPRENORPHINE Cause?
Drug dependence (16,730)
Overdose (13,977)
Death (13,604)
Toxicity to various agents (10,906)
Pain (8,219)
Drug withdrawal syndrome (7,149)
Emotional distress (6,159)
Drug abuse (4,344)
Drug ineffective (4,261)
Dependence (3,184)
What Other Drugs Cause Malaise?
ADALIMUMAB (15,965)
ETANERCEPT (13,600)
METHOTREXATE (9,970)
TOFACITINIB (9,040)
SECUKINUMAB (8,570)
INFLIXIMAB (7,477)
RITUXIMAB (6,587)
PREGABALIN (6,320)
PREDNISONE (6,319)
ABATACEPT (6,251)
Which BUPRENORPHINE Alternatives Have Lower Malaise Risk?
BUPRENORPHINE vs BUPRENORPHINE\NALOXONE
BUPRENORPHINE vs BUPROPION
BUPRENORPHINE vs BUPROPION HYDROBROMIDE
BUPRENORPHINE vs BUPROPION\DEXTROMETHORPHAN HYDROBROMIDE
BUPRENORPHINE vs BUPROPION\NALTREXONE