Does BUPROPION Cause Methaemoglobinaemia? 25 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 25 reports of Methaemoglobinaemia have been filed in association with BUPROPION (Bupropion Hydrochloride (XL)). This represents 0.1% of all adverse event reports for BUPROPION.
25
Reports of Methaemoglobinaemia with BUPROPION
0.1%
of all BUPROPION reports
5
Deaths
24
Hospitalizations
How Dangerous Is Methaemoglobinaemia From BUPROPION?
Of the 25 reports, 5 (20.0%) resulted in death, 24 (96.0%) required hospitalization, and 1 (4.0%) were considered life-threatening.
Is Methaemoglobinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUPROPION. However, 25 reports have been filed with the FAERS database.
What Other Side Effects Does BUPROPION Cause?
Completed suicide (5,095)
Drug ineffective (3,991)
Toxicity to various agents (3,837)
Depression (2,486)
Overdose (2,357)
Headache (2,323)
Anxiety (2,145)
Intentional overdose (2,103)
Drug hypersensitivity (1,967)
Seizure (1,894)
What Other Drugs Cause Methaemoglobinaemia?
DAPSONE (322)
LIDOCAINE (221)
ACETAMINOPHEN (186)
BENZOCAINE (162)
RASBURICASE (92)
SULFAMETHOXAZOLE\TRIMETHOPRIM (86)
LIDOCAINE\PRILOCAINE (67)
PRIMAQUINE (56)
HYDROXYCHLOROQUINE (54)
MEROPENEM (46)
Which BUPROPION Alternatives Have Lower Methaemoglobinaemia Risk?
BUPROPION vs BUPROPION HYDROBROMIDE
BUPROPION vs BUPROPION\DEXTROMETHORPHAN HYDROBROMIDE
BUPROPION vs BUPROPION\NALTREXONE
BUPROPION vs BUROSUMAB
BUPROPION vs BUROSUMAB-TWZA