Does BUPROPION Cause Off label use? 1,514 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,514 reports of Off label use have been filed in association with BUPROPION (Bupropion Hydrochloride (XL)). This represents 4.3% of all adverse event reports for BUPROPION.
1,514
Reports of Off label use with BUPROPION
4.3%
of all BUPROPION reports
141
Deaths
410
Hospitalizations
How Dangerous Is Off label use From BUPROPION?
Of the 1,514 reports, 141 (9.3%) resulted in death, 410 (27.1%) required hospitalization, and 68 (4.5%) were considered life-threatening.
Is Off label use Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUPROPION. However, 1,514 reports have been filed with the FAERS database.
What Other Side Effects Does BUPROPION Cause?
Completed suicide (5,095)
Drug ineffective (3,991)
Toxicity to various agents (3,837)
Depression (2,486)
Overdose (2,357)
Headache (2,323)
Anxiety (2,145)
Intentional overdose (2,103)
Drug hypersensitivity (1,967)
Seizure (1,894)
What Other Drugs Cause Off label use?
RITUXIMAB (39,751)
INFLIXIMAB (34,801)
DENOSUMAB (34,612)
METHOTREXATE (24,020)
VEDOLIZUMAB (21,017)
ETANERCEPT (20,178)
TOCILIZUMAB (18,256)
PREDNISONE (17,867)
LENALIDOMIDE (17,017)
ADALIMUMAB (16,417)
Which BUPROPION Alternatives Have Lower Off label use Risk?
BUPROPION vs BUPROPION HYDROBROMIDE
BUPROPION vs BUPROPION\DEXTROMETHORPHAN HYDROBROMIDE
BUPROPION vs BUPROPION\NALTREXONE
BUPROPION vs BUROSUMAB
BUPROPION vs BUROSUMAB-TWZA