Does BUSULFAN Cause Pancytopenia? 333 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 333 reports of Pancytopenia have been filed in association with BUSULFAN (Busulfan). This represents 3.0% of all adverse event reports for BUSULFAN.
333
Reports of Pancytopenia with BUSULFAN
3.0%
of all BUSULFAN reports
68
Deaths
117
Hospitalizations
How Dangerous Is Pancytopenia From BUSULFAN?
Of the 333 reports, 68 (20.4%) resulted in death, 117 (35.1%) required hospitalization, and 13 (3.9%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUSULFAN. However, 333 reports have been filed with the FAERS database.
What Other Side Effects Does BUSULFAN Cause?
Off label use (1,402)
Product use in unapproved indication (1,387)
Mucosal inflammation (880)
Venoocclusive liver disease (765)
Febrile neutropenia (628)
Cytomegalovirus infection (620)
Drug ineffective (569)
Graft versus host disease (507)
Pyrexia (502)
Cytomegalovirus infection reactivation (481)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which BUSULFAN Alternatives Have Lower Pancytopenia Risk?
BUSULFAN vs BUSULFEX
BUSULFAN vs BUTALBITAL
BUSULFAN vs BUTENAFINE
BUSULFAN vs BUTORPHANOL
BUSULFAN vs BUTRANS