Does CARBOPLATIN Cause Cholestasis? 295 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 295 reports of Cholestasis have been filed in association with CARBOPLATIN (Carboplatin). This represents 0.4% of all adverse event reports for CARBOPLATIN.
295
Reports of Cholestasis with CARBOPLATIN
0.4%
of all CARBOPLATIN reports
16
Deaths
140
Hospitalizations
How Dangerous Is Cholestasis From CARBOPLATIN?
Of the 295 reports, 16 (5.4%) resulted in death, 140 (47.5%) required hospitalization, and 14 (4.7%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CARBOPLATIN. However, 295 reports have been filed with the FAERS database.
What Other Side Effects Does CARBOPLATIN Cause?
Off label use (6,100)
Neutropenia (5,314)
Anaemia (5,312)
Febrile neutropenia (4,888)
Nausea (4,588)
Disease progression (4,538)
Thrombocytopenia (4,483)
Malignant neoplasm progression (4,177)
Diarrhoea (4,154)
Dyspnoea (3,494)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which CARBOPLATIN Alternatives Have Lower Cholestasis Risk?
CARBOPLATIN vs CARBOPROST TROMETHAMINE
CARBOPLATIN vs CARBOXYMETHYLCELLULOSE
CARBOPLATIN vs CARBOXYMETHYLCELLULOSE\GLYCERIN
CARBOPLATIN vs CARBOXYMETHYLCELLULOSE\GLYCERIN\POLYSORBATE 80
CARBOPLATIN vs CARBOXYMETHYLCELLULOSE\HYPROMELLOSES