CARFILZOMIB for Immune tolerance induction: Side Effects & Safety Data
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There are 23 adverse event reports in the FDA FAERS database where CARFILZOMIB was used for Immune tolerance induction.
Most Reported Side Effects for CARFILZOMIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Plasma cell myeloma | 2,238 | 10.3% | 748 | 426 |
| Off label use | 2,120 | 9.7% | 361 | 393 |
| Death | 1,442 | 6.6% | 1,441 | 249 |
| Thrombocytopenia | 1,265 | 5.8% | 284 | 385 |
| Fatigue | 1,048 | 4.8% | 131 | 205 |
| Pneumonia | 1,016 | 4.7% | 334 | 634 |
| Pyrexia | 969 | 4.4% | 170 | 590 |
| Anaemia | 910 | 4.2% | 212 | 373 |
| Dyspnoea | 881 | 4.0% | 141 | 338 |
| Neutropenia | 874 | 4.0% | 190 | 213 |
| Diarrhoea | 764 | 3.5% | 157 | 285 |
| Acute kidney injury | 746 | 3.4% | 201 | 493 |
| Nausea | 707 | 3.2% | 113 | 194 |
| Disease progression | 622 | 2.9% | 166 | 144 |
| Hypertension | 609 | 2.8% | 127 | 228 |
Other Indications for CARFILZOMIB
Plasma cell myeloma (15,333)
Product used for unknown indication (4,210)
Plasma cell myeloma refractory (1,208)
Plasma cell leukaemia (186)
Off label use (143)
Acute lymphocytic leukaemia (86)
Plasma cell myeloma recurrent (66)
Plasmacytoma (66)
Chemotherapy (51)
Amyloidosis (44)
Other Drugs Used for Immune tolerance induction
RITUXIMAB (207)
HUMAN IMMUNOGLOBULIN G (88)
ASPIRIN (62)
MYCOPHENOLATE MOFETIL (62)
ANTIHEMOPHILIC FACTOR, HUMAN RECOMBINANT (53)
--BLOOD-COAGULATION FACTOR VIII FUSION PROTEIN WITH IMMUNOGLOBULIN G1 , ,-BIS WITH IMMUNOGLOBULIN G1 (52)
EFMOROCTOCOG ALFA (46)
PHLEUM PRATENSE POLLEN (36)
BORTEZOMIB (35)
OXALIPLATIN (33)