Does CARFILZOMIB Cause Off label use? 2,120 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,120 reports of Off label use have been filed in association with CARFILZOMIB (KYPROLIS). This represents 9.7% of all adverse event reports for CARFILZOMIB.
2,120
Reports of Off label use with CARFILZOMIB
9.7%
of all CARFILZOMIB reports
361
Deaths
393
Hospitalizations
How Dangerous Is Off label use From CARFILZOMIB?
Of the 2,120 reports, 361 (17.0%) resulted in death, 393 (18.5%) required hospitalization, and 113 (5.3%) were considered life-threatening.
Is Off label use Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CARFILZOMIB. However, 2,120 reports have been filed with the FAERS database.
What Other Side Effects Does CARFILZOMIB Cause?
Plasma cell myeloma (2,238)
Death (1,442)
Thrombocytopenia (1,265)
Fatigue (1,048)
Pneumonia (1,016)
Pyrexia (969)
Anaemia (910)
Dyspnoea (881)
Neutropenia (874)
Diarrhoea (764)
What Other Drugs Cause Off label use?
RITUXIMAB (39,751)
INFLIXIMAB (34,801)
DENOSUMAB (34,612)
METHOTREXATE (24,020)
VEDOLIZUMAB (21,017)
ETANERCEPT (20,178)
TOCILIZUMAB (18,256)
PREDNISONE (17,867)
LENALIDOMIDE (17,017)
ADALIMUMAB (16,417)
Which CARFILZOMIB Alternatives Have Lower Off label use Risk?
CARFILZOMIB vs CARGLUMIC ACID
CARFILZOMIB vs CARIPRAZINE
CARFILZOMIB vs CARISOPRODOL
CARFILZOMIB vs CARMUSTINE
CARFILZOMIB vs CARTEOLOL