CARFILZOMIB for Prophylaxis: Side Effects & Safety Data
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There are 6 adverse event reports in the FDA FAERS database where CARFILZOMIB was used for Prophylaxis.
Most Reported Side Effects for CARFILZOMIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Plasma cell myeloma | 2,238 | 10.3% | 748 | 426 |
| Off label use | 2,120 | 9.7% | 361 | 393 |
| Death | 1,442 | 6.6% | 1,441 | 249 |
| Thrombocytopenia | 1,265 | 5.8% | 284 | 385 |
| Fatigue | 1,048 | 4.8% | 131 | 205 |
| Pneumonia | 1,016 | 4.7% | 334 | 634 |
| Pyrexia | 969 | 4.4% | 170 | 590 |
| Anaemia | 910 | 4.2% | 212 | 373 |
| Dyspnoea | 881 | 4.0% | 141 | 338 |
| Neutropenia | 874 | 4.0% | 190 | 213 |
| Diarrhoea | 764 | 3.5% | 157 | 285 |
| Acute kidney injury | 746 | 3.4% | 201 | 493 |
| Nausea | 707 | 3.2% | 113 | 194 |
| Disease progression | 622 | 2.9% | 166 | 144 |
| Hypertension | 609 | 2.8% | 127 | 228 |
Other Indications for CARFILZOMIB
Plasma cell myeloma (15,333)
Product used for unknown indication (4,210)
Plasma cell myeloma refractory (1,208)
Plasma cell leukaemia (186)
Off label use (143)
Acute lymphocytic leukaemia (86)
Plasma cell myeloma recurrent (66)
Plasmacytoma (66)
Chemotherapy (51)
Amyloidosis (44)
Other Drugs Used for Prophylaxis
PEGFILGRASTIM (7,424)
HUMAN C1-ESTERASE INHIBITOR (5,950)
DENOSUMAB (4,541)
SULFAMETHOXAZOLE\TRIMETHOPRIM (3,197)
ASPIRIN (2,083)
VALACYCLOVIR (1,574)
PANTOPRAZOLE (1,502)
VARICELLA-ZOSTER VIRUS STRAIN OKA/MERCK LIVE ANTIGEN (1,444)
CLOPIDOGREL BISULFATE (1,296)
ENOXAPARIN (1,278)