Does CEFEPIME Cause Cholestasis? 68 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 68 reports of Cholestasis have been filed in association with CEFEPIME (Cefepime). This represents 1.2% of all adverse event reports for CEFEPIME.
68
Reports of Cholestasis with CEFEPIME
1.2%
of all CEFEPIME reports
3
Deaths
58
Hospitalizations
How Dangerous Is Cholestasis From CEFEPIME?
Of the 68 reports, 3 (4.4%) resulted in death, 58 (85.3%) required hospitalization, and 3 (4.4%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
Yes, Cholestasis is listed as a known adverse reaction in the official FDA drug label for CEFEPIME.
What Other Side Effects Does CEFEPIME Cause?
Drug ineffective (864)
Acute kidney injury (706)
Off label use (383)
Encephalopathy (376)
Drug reaction with eosinophilia and systemic symptoms (288)
Condition aggravated (242)
Confusional state (207)
Rash (194)
Pyrexia (185)
Thrombocytopenia (181)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which CEFEPIME Alternatives Have Lower Cholestasis Risk?
CEFEPIME vs CEFEPIME\CEFEPIME
CEFEPIME vs CEFIDEROCOL
CEFEPIME vs CEFIXIME
CEFEPIME vs CEFMETAZOLE
CEFEPIME vs CEFOPERAZONE