Does CHLORAMBUCIL Cause Malignant transformation? 25 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 25 reports of Malignant transformation have been filed in association with CHLORAMBUCIL (LEUKERAN). This represents 1.1% of all adverse event reports for CHLORAMBUCIL.
25
Reports of Malignant transformation with CHLORAMBUCIL
1.1%
of all CHLORAMBUCIL reports
21
Deaths
0
Hospitalizations
How Dangerous Is Malignant transformation From CHLORAMBUCIL?
Of the 25 reports, 21 (84.0%) resulted in death.
Is Malignant transformation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CHLORAMBUCIL. However, 25 reports have been filed with the FAERS database.
What Other Side Effects Does CHLORAMBUCIL Cause?
Off label use (176)
Neutropenia (173)
Pneumonia (158)
Pyrexia (132)
Acute myeloid leukaemia (107)
Disease progression (104)
Drug ineffective (103)
Febrile neutropenia (94)
Thrombocytopenia (93)
Myositis (89)
What Other Drugs Cause Malignant transformation?
OSIMERTINIB (109)
ETOPOSIDE (108)
MELPHALAN (95)
CYTARABINE (91)
CARMUSTINE (88)
CYCLOPHOSPHAMIDE (73)
PREDNISONE (69)
GEFITINIB (67)
VINCRISTINE (66)
DOXORUBICIN (61)
Which CHLORAMBUCIL Alternatives Have Lower Malignant transformation Risk?
CHLORAMBUCIL vs CHLORAMPHENICOL
CHLORAMBUCIL vs CHLORDIAZEPOXIDE
CHLORAMBUCIL vs CHLORDIAZEPOXIDE\CLIDINIUM
CHLORAMBUCIL vs CHLORHEXIDINE
CHLORAMBUCIL vs CHLORHEXIDINE\CHLORHEXIDINE