Does CHLORAMBUCIL Cause Off label use? 176 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 176 reports of Off label use have been filed in association with CHLORAMBUCIL (LEUKERAN). This represents 7.7% of all adverse event reports for CHLORAMBUCIL.
176
Reports of Off label use with CHLORAMBUCIL
7.7%
of all CHLORAMBUCIL reports
44
Deaths
63
Hospitalizations
How Dangerous Is Off label use From CHLORAMBUCIL?
Of the 176 reports, 44 (25.0%) resulted in death, 63 (35.8%) required hospitalization, and 7 (4.0%) were considered life-threatening.
Is Off label use Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CHLORAMBUCIL. However, 176 reports have been filed with the FAERS database.
What Other Side Effects Does CHLORAMBUCIL Cause?
Neutropenia (173)
Pneumonia (158)
Pyrexia (132)
Acute myeloid leukaemia (107)
Disease progression (104)
Drug ineffective (103)
Febrile neutropenia (94)
Thrombocytopenia (93)
Myositis (89)
Second primary malignancy (76)
What Other Drugs Cause Off label use?
RITUXIMAB (39,751)
INFLIXIMAB (34,801)
DENOSUMAB (34,612)
METHOTREXATE (24,020)
VEDOLIZUMAB (21,017)
ETANERCEPT (20,178)
TOCILIZUMAB (18,256)
PREDNISONE (17,867)
LENALIDOMIDE (17,017)
ADALIMUMAB (16,417)
Which CHLORAMBUCIL Alternatives Have Lower Off label use Risk?
CHLORAMBUCIL vs CHLORAMPHENICOL
CHLORAMBUCIL vs CHLORDIAZEPOXIDE
CHLORAMBUCIL vs CHLORDIAZEPOXIDE\CLIDINIUM
CHLORAMBUCIL vs CHLORHEXIDINE
CHLORAMBUCIL vs CHLORHEXIDINE\CHLORHEXIDINE