Does CHLORAMBUCIL Cause Second primary malignancy? 76 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 76 reports of Second primary malignancy have been filed in association with CHLORAMBUCIL (LEUKERAN). This represents 3.3% of all adverse event reports for CHLORAMBUCIL.
76
Reports of Second primary malignancy with CHLORAMBUCIL
3.3%
of all CHLORAMBUCIL reports
49
Deaths
33
Hospitalizations
How Dangerous Is Second primary malignancy From CHLORAMBUCIL?
Of the 76 reports, 49 (64.5%) resulted in death, 33 (43.4%) required hospitalization, and 1 (1.3%) were considered life-threatening.
Is Second primary malignancy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CHLORAMBUCIL. However, 76 reports have been filed with the FAERS database.
What Other Side Effects Does CHLORAMBUCIL Cause?
Off label use (176)
Neutropenia (173)
Pneumonia (158)
Pyrexia (132)
Acute myeloid leukaemia (107)
Disease progression (104)
Drug ineffective (103)
Febrile neutropenia (94)
Thrombocytopenia (93)
Myositis (89)
What Other Drugs Cause Second primary malignancy?
CYCLOPHOSPHAMIDE (1,247)
DOXORUBICIN (1,151)
VINCRISTINE (908)
IMATINIB (763)
PALBOCICLIB (658)
RITUXIMAB (646)
RUXOLITINIB (611)
ETOPOSIDE (573)
PREDNISONE (517)
OCTREOTIDE (496)
Which CHLORAMBUCIL Alternatives Have Lower Second primary malignancy Risk?
CHLORAMBUCIL vs CHLORAMPHENICOL
CHLORAMBUCIL vs CHLORDIAZEPOXIDE
CHLORAMBUCIL vs CHLORDIAZEPOXIDE\CLIDINIUM
CHLORAMBUCIL vs CHLORHEXIDINE
CHLORAMBUCIL vs CHLORHEXIDINE\CHLORHEXIDINE