Does CHLORAMBUCIL Cause Sepsis? 52 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 52 reports of Sepsis have been filed in association with CHLORAMBUCIL (LEUKERAN). This represents 2.3% of all adverse event reports for CHLORAMBUCIL.
52
Reports of Sepsis with CHLORAMBUCIL
2.3%
of all CHLORAMBUCIL reports
34
Deaths
21
Hospitalizations
How Dangerous Is Sepsis From CHLORAMBUCIL?
Of the 52 reports, 34 (65.4%) resulted in death, 21 (40.4%) required hospitalization, and 13 (25.0%) were considered life-threatening.
Is Sepsis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CHLORAMBUCIL. However, 52 reports have been filed with the FAERS database.
What Other Side Effects Does CHLORAMBUCIL Cause?
Off label use (176)
Neutropenia (173)
Pneumonia (158)
Pyrexia (132)
Acute myeloid leukaemia (107)
Disease progression (104)
Drug ineffective (103)
Febrile neutropenia (94)
Thrombocytopenia (93)
Myositis (89)
What Other Drugs Cause Sepsis?
RITUXIMAB (4,043)
CYCLOPHOSPHAMIDE (4,041)
METHOTREXATE (3,933)
ADALIMUMAB (3,169)
DEXAMETHASONE (3,150)
LENALIDOMIDE (2,956)
VINCRISTINE (2,791)
DOXORUBICIN (2,740)
PREDNISONE (2,634)
PREDNISOLONE (2,281)
Which CHLORAMBUCIL Alternatives Have Lower Sepsis Risk?
CHLORAMBUCIL vs CHLORAMPHENICOL
CHLORAMBUCIL vs CHLORDIAZEPOXIDE
CHLORAMBUCIL vs CHLORDIAZEPOXIDE\CLIDINIUM
CHLORAMBUCIL vs CHLORHEXIDINE
CHLORAMBUCIL vs CHLORHEXIDINE\CHLORHEXIDINE