Does CHLORPHENIRAMINE Cause Serotonin syndrome? 36 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 36 reports of Serotonin syndrome have been filed in association with CHLORPHENIRAMINE (ACTIDOM DA). This represents 1.9% of all adverse event reports for CHLORPHENIRAMINE.
36
Reports of Serotonin syndrome with CHLORPHENIRAMINE
1.9%
of all CHLORPHENIRAMINE reports
10
Deaths
15
Hospitalizations
How Dangerous Is Serotonin syndrome From CHLORPHENIRAMINE?
Of the 36 reports, 10 (27.8%) resulted in death, 15 (41.7%) required hospitalization, and 6 (16.7%) were considered life-threatening.
Is Serotonin syndrome Listed in the Official Label?
Yes, Serotonin syndrome is listed as a known adverse reaction in the official FDA drug label for CHLORPHENIRAMINE.
What Other Side Effects Does CHLORPHENIRAMINE Cause?
Toxicity to various agents (286)
Off label use (189)
Drug abuse (179)
Drug ineffective (167)
Dyspnoea (148)
Somnolence (147)
Vomiting (146)
Drug hypersensitivity (126)
Nausea (122)
Headache (119)
What Other Drugs Cause Serotonin syndrome?
VENLAFAXINE (1,632)
SERTRALINE (1,563)
FLUOXETINE (1,457)
DULOXETINE (1,352)
TRAMADOL (1,229)
BUPROPION (1,058)
ESCITALOPRAM OXALATE (1,051)
QUETIAPINE (947)
TRAZODONE (831)
FENTANYL (778)
Which CHLORPHENIRAMINE Alternatives Have Lower Serotonin syndrome Risk?
CHLORPHENIRAMINE vs CHLORPHENIRAMINE\CODEINE\PSEUDOEPHEDRINE
CHLORPHENIRAMINE vs CHLORPHENIRAMINE\DEXTROMETHORPHAN HYDROBROMIDE
CHLORPHENIRAMINE vs CHLORPHENIRAMINE\HYDROCODONE
CHLORPHENIRAMINE vs CHLORPHENIRAMINE\HYDROCODONE\PSEUDOEPHEDRINE
CHLORPHENIRAMINE vs CHLORPHENIRAMINE\IBUPROFEN\PHENYLEPHRINE