Does CHLORTHALIDONE Cause Cholestasis? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Cholestasis have been filed in association with CHLORTHALIDONE (Chlorthalidone). This represents 0.4% of all adverse event reports for CHLORTHALIDONE.
6
Reports of Cholestasis with CHLORTHALIDONE
0.4%
of all CHLORTHALIDONE reports
2
Deaths
5
Hospitalizations
How Dangerous Is Cholestasis From CHLORTHALIDONE?
Of the 6 reports, 2 (33.3%) resulted in death, 5 (83.3%) required hospitalization.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CHLORTHALIDONE. However, 6 reports have been filed with the FAERS database.
What Other Side Effects Does CHLORTHALIDONE Cause?
Hyponatraemia (258)
Drug ineffective (209)
Nausea (159)
Hypokalaemia (136)
Dizziness (133)
Acute kidney injury (126)
Oedema peripheral (114)
Vomiting (107)
Hypotension (102)
Dyspnoea (96)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which CHLORTHALIDONE Alternatives Have Lower Cholestasis Risk?
CHLORTHALIDONE vs CHLORZOXAZONE
CHLORTHALIDONE vs CHOLECALCIFEROL
CHLORTHALIDONE vs CHOLECALCIFEROL\ERGOCALCIFEROL
CHLORTHALIDONE vs CHOLESTYRAMINE
CHLORTHALIDONE vs CHOLIC ACID