Does CLOFARABINE Cause Bone marrow failure? 63 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 63 reports of Bone marrow failure have been filed in association with CLOFARABINE (Clofarabine). This represents 4.4% of all adverse event reports for CLOFARABINE.
63
Reports of Bone marrow failure with CLOFARABINE
4.4%
of all CLOFARABINE reports
37
Deaths
13
Hospitalizations
How Dangerous Is Bone marrow failure From CLOFARABINE?
Of the 63 reports, 37 (58.7%) resulted in death, 13 (20.6%) required hospitalization, and 11 (17.5%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CLOFARABINE. However, 63 reports have been filed with the FAERS database.
What Other Side Effects Does CLOFARABINE Cause?
Febrile neutropenia (201)
Off label use (158)
Drug ineffective (139)
Pyrexia (139)
Mucosal inflammation (89)
Sepsis (85)
Alanine aminotransferase increased (82)
Acute kidney injury (80)
Multiple organ dysfunction syndrome (77)
Aspartate aminotransferase increased (76)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which CLOFARABINE Alternatives Have Lower Bone marrow failure Risk?
CLOFARABINE vs CLOFAZIMINE
CLOFARABINE vs CLOMETHIAZOLE
CLOFARABINE vs CLOMIPHENE
CLOFARABINE vs CLOMIPRAMINE
CLOFARABINE vs CLONAZEPAM