Does CLOZAPINE Cause Disinhibition? 171 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 171 reports of Disinhibition have been filed in association with CLOZAPINE (CLOZAPINE). This represents 0.2% of all adverse event reports for CLOZAPINE.
171
Reports of Disinhibition with CLOZAPINE
0.2%
of all CLOZAPINE reports
2
Deaths
166
Hospitalizations
How Dangerous Is Disinhibition From CLOZAPINE?
Of the 171 reports, 2 (1.2%) resulted in death, 166 (97.1%) required hospitalization, and 1 (0.6%) were considered life-threatening.
Is Disinhibition Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CLOZAPINE. However, 171 reports have been filed with the FAERS database.
What Other Side Effects Does CLOZAPINE Cause?
Neutropenia (18,981)
Hospitalisation (12,144)
Death (9,500)
Schizophrenia (3,991)
White blood cell count decreased (3,454)
Off label use (3,192)
Neutrophil count increased (3,125)
Drug ineffective (3,105)
Neutrophilia (3,105)
White blood cell count increased (2,988)
What Other Drugs Cause Disinhibition?
ARIPIPRAZOLE (233)
OLANZAPINE (215)
QUETIAPINE (194)
AMISULPRIDE (169)
FLUOXETINE (169)
RISPERIDONE (168)
LITHIUM (164)
GABAPENTIN (163)
CITALOPRAM HYDROBROMIDE (157)
LOXAPINE (157)
Which CLOZAPINE Alternatives Have Lower Disinhibition Risk?
CLOZAPINE vs CLOZARIL
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTEIN C\PROTEIN S HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN\ISOPROPYL ALCOHOL