Disinhibition: Which Medications Cause It? (1,047 Reports Across 92 Drugs)
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Disinhibition has been reported as an adverse event with 92 different drugs in the FDA's FAERS database, with 1,047 total reports. 26 of these reports resulted in death.The drugs most commonly associated with Disinhibition are ARIPIPRAZOLE, OLANZAPINE, and QUETIAPINE.
1,047
Total Reports
92
Drugs Involved
26
Deaths
518
Hospitalizations
43.0 yrs
Average Patient Age
35.1% / 64.9%
Female / Male
Which Drugs Cause Disinhibition Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ARIPIPRAZOLE | 233 | 0.4% | 0 | 188 | 1 |
| OLANZAPINE | 215 | 0.4% | 4 | 177 | 2 |
| QUETIAPINE | 194 | 0.3% | 5 | 160 | 1 |
| CLOZAPINE | 171 | 0.2% | 2 | 166 | 1 |
| AMISULPRIDE | 169 | 5.4% | 0 | 160 | 1 |
| FLUOXETINE | 169 | 0.5% | 0 | 163 | 6 |
| RISPERIDONE | 168 | 0.2% | 1 | 162 | 2 |
| LITHIUM | 164 | 1.1% | 0 | 162 | 1 |
| GABAPENTIN | 163 | 0.2% | 0 | 160 | 1 |
| CITALOPRAM HYDROBROMIDE | 157 | 0.6% | 3 | 138 | 5 |
| LOXAPINE | 157 | 3.6% | 0 | 157 | 1 |
| CLOMIPRAMINE | 156 | 4.1% | 0 | 154 | 1 |
| FLUPENTIXOL | 153 | 13.4% | 0 | 153 | 1 |
| ZIPRASIDONE | 153 | 4.3% | 0 | 153 | 1 |
| ASENAPINE | 152 | 5.3% | 0 | 152 | 1 |
| THIORIDAZINE | 151 | 35.6% | 0 | 151 | 1 |
| PERPHENAZINE | 148 | 16.0% | 0 | 148 | 1 |
| TRIFLUOPERAZINE | 145 | 39.3% | 0 | 145 | 1 |
| HALOPERIDOL | 141 | 0.9% | 3 | 137 | 1 |
| SERTRALINE | 64 | 0.1% | 0 | 20 | 0 |